What is the Connection between Niacin Difficiency and Alzheimer’s Disease and Dementia?

Eldercare Advice Blog

Reduced intake of the B vitamin niacin may predispose elderly people to develop Alzheimers disease, according to a study presented at the 2002 Gerontological Society of Americas 55th Annual Scientific Meeting.

In the study, the researchers determined food intake by use of a questionnaire in which 815 healthy participants indicated the frequency with which they consumed niacin-rich foods. The researchers then determined how much niacin the subjects, who were at least 65 years old, consumed. The researchers followed up to determine which subjects developed Alzheimers over the next 4 years.


The findings indicate that people who received the most niacin in their diets were 79% less likely to develop Alzheimer’s than those who consumed the lowest intake of niacin. Half of the subjects who fell into low risk for Alzheimer’s consumed more than 22 mg of niacin daily. Of those subjects who consumed the lowest amount of niacin, half…

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